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Search Results for " transforming growth factor, β1 "
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Targets Recommended: TGF-beta/Smad

6

抑制剂 & 化合物

1

天然产物

1

化合物库

14

重组蛋白

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Cat. No. Product Name
L4100 TGF-β/Smad靶点化合物库

184 compounds
184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合,用于高通量、高内涵筛选;

化合物库

TGF-β/Smad靶点化合物库
Cat.No: L4100
Compounds: 184
Cat. No. Product Name Target Signaling Pathways
T3636 (E)-SIS3

SIS3,SIS3 盐酸盐,SIS3 HCl

TGF-beta/Smad Stem Cells
(E)-SIS3 (SIS3) 是 Smad3 的选择性抑制剂,能够抑制 Smad3 磷酸化(IC50:3 μM)。它利用 TGF-β1 抑制成纤维细胞向肌成纤维细胞分化。
T11052L Disitertide acetate

P144 acetate,Disitertide acetate(272105-42-7 Free base)

TGF-beta/Smad Stem Cells
Disitertide acetate (P144 acetate) 是转化生长因子 TGFβ1 的多肽抑制剂,特异性的阻断其与受体间的相互作用。Disitertide acetate 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。
T80272 Vicatertide

SB-01

Vicatertide为TGF beta-1抑制剂。
T79603 3,7-DMF

TGF-beta/Smad Stem Cells
3,7-DMF作为一种口服活性抑制剂,有效抑制了TGF-β1诱导的HSC活化,并通过诱导抗氧化基因及淬灭ROS为研究肝纤维化提供了潜在应用。
T75716 Disitertide TFA

Disitertide (P144) TFA 是转化生长因子TGFβ1的多肽抑制剂,特异性的阻断其与受体间的相互作用。Disitertide TFA 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。
T75717 Disitertide diammonium

Disitertide (P144) diammonium 是转化生长因子TGFβ1的多肽抑制剂,特异性的阻断其与受体间的相互作用。Disitertide diammonium 也是PI3K 的抑制剂和凋亡 (apoptosis) 诱导剂。

化合物

(E)-SIS3
Cat.No: T3636
Synonym: SIS3,SIS3 盐酸盐,SIS3 HCl
Target: TGF-beta/Smad
Disitertide acetate
Cat.No: T11052L
Synonym: P144 acetate,Disitertide acetate(272105-42-7 Free base)
Target: TGF-beta/Smad
Vicatertide
Cat.No: T80272
Synonym: SB-01
Target:
3,7-DMF
Cat.No: T79603
Synonym:
Target: TGF-beta/Smad
Disitertide TFA
Cat.No: T75716
Synonym:
Target:
Disitertide diammonium
Cat.No: T75717
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T13741 Isoviolanthin

异佛莱心苷,异佛来心苷

Others Others
Isoviolanthin 是一种黄酮类苷类化合物,提取自铁皮石斛叶中。它能减少 TGF-β1 处理的 HCC 细胞的迁移和入侵能力,对正常细胞没有毒性影响,对转移性肝癌晚期具有潜在的研究价值。

天然产物

Isoviolanthin
Cat.No: T13741
Synonym: 异佛莱心苷,异佛来心苷
Target: Others
Cat. No. Product Name Species Expression System
TMPY-02638 TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant

transforming growth factor, beta ...

Human,Rhesus,Cynomolgus,Canine CHO Cells
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 12.8 kDa and the accession number is A0A499FJK2.
TMPY-00608 TGF beta 1 Protein, Rat/Mouse, Recombinant

transforming growth factor, beta ...

Mouse,Rat HEK293 Cells
TGF beta 1 Protein, Rat/Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.8 kDa.
TMPY-04211 Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)

transforming growth factor, β...

Cynomolgus HEK293 Cells
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa.
TMPY-03945 Latent TGF beta 1 Protein, Rat, Recombinant (His)

TGF β1,transforming growth fa...

Rat HEK293 Cells
Latent TGF beta 1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P17246.
TMPY-00500 Latent TGF beta 1 Protein, Mouse, Recombinant (His)

transforming growth factor, beta ...

Mouse HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.
TMPY-01133 Latent TGF beta 1 Protein, Human, Recombinant (His)

CED,DPD1,transforming growth factor

Human HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPJ-00249 TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated

TGF-Beta-1,TGFB1,Transforming Growth F...

Human HEK293 Cells
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family...
TMPY-00229 Latent TGF beta 1 Protein, Canine, Recombinant (His)

transforming growth factor, β...

Canine HEK293 Cells
Latent TGF beta 1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.4 kDa.
TMPY-05313 Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated

transforming growth factor, beta ...

Mouse HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202.
TMPY-05521 Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated

TGFB,TGF β1,转化生长因子,TGF-beta 1,transforming...

Human HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPJ-00772 Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Transforming growth factor β-1,La...

Mouse HEK293 Cells
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 35-45 KDa and the accession number is P04202.
TMPJ-00622 Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)

转化生长因子,Transforming growth factor...

Cynomolgus HEK293 Cells
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 11 and 35-45 KDa and the accession number is F7HCV5.
TMPJ-00250 LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated

transforming growth factor β1...

Human HEK293 Cells
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activation of these complexes is a critical step in regulation of TGFβ function in vivo. The TGFβ1 LAP is a ligand for the integrin αvβ6 and that αvβ6-expressing cells induce spatially restricted activition of TGFβ1. And LAP identifies a novel CD4+/CD25+ regulatory T cell subset with ...
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant

TGFB,TGFbeta,CEDLAP,TGF-beta-1,TGF-beta 1 protein,latency-as...

Mouse,Rat HEK293 Cells
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II)...

重组蛋白

TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
Cat.No: TMPY-02638
Species: Human,Rhesus,Cynomolgus,Canine
Expression System: CHO Cells
TGF beta 1 Protein, Rat/Mouse, Recombinant
Cat.No: TMPY-00608
Species: Mouse,Rat
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-04211
Species: Cynomolgus
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03945
Species: Rat
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00500
Species: Mouse
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01133
Species: Human
Expression System: HEK293 Cells
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
Cat.No: TMPJ-00249
Species: Human
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Canine, Recombinant (His)
Cat.No: TMPY-00229
Species: Canine
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-05313
Species: Mouse
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05521
Species: Human
Expression System: HEK293 Cells
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00772
Species: Mouse
Expression System: HEK293 Cells
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00622
Species: Cynomolgus
Expression System: HEK293 Cells
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00250
Species: Human
Expression System: HEK293 Cells
TGF beta 1 Protein, Mouse/Rat, Recombinant
Cat.No: TMPJ-00771
Species: Mouse,Rat
Expression System: HEK293 Cells
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